Pre-transplant Rehabilitation to Decrease the Post-transplant Length of Stay for Hematological Malignancy Patients...

Area of Science:

• Hematology
• Oncology
• Rehabilitation Medicine

Background:

• Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a critical treatment for hematological malignancies.
• Pre-transplant rehabilitation aims to enhance physical capacity before intensive medical procedures.
• The impact of pre-transplant rehabilitation on post-transplant hospital length of stay (LOS) remains insufficiently understood.

Purpose of the Study:

• To investigate the effect of pre-transplant rehabilitation on post-transplant LOS in patients with hematological malignancies undergoing allo-HSCT.

Main Methods:

• Retrospective analysis of patient data from the Japanese Diagnosis Procedure Combination database (April 2014 - March 2017).
• Identification of patients using ICD-10 codes for hematological malignancies.
• Multilevel linear regression models were employed to assess the association between pre-transplant rehabilitation and post-transplant LOS.

Main Results:

• A total of 3614 patients were included in the analysis.
• Pre-transplant rehabilitation was significantly associated with a reduction in post-transplant hospital LOS (β=-0.134, P<0.001).

Conclusions:

• Pre-transplant rehabilitation emerges as a potentially effective strategy for shortening post-transplant hospital LOS.
• Implementing rehabilitation programs prior to allo-HSCT may be a valuable consideration for improving patient recovery trajectories.