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Updated: Nov 7, 2025

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
Published on: August 30, 2013
OPTIMAM Mammography Image Database: A Large-Scale Resource of Mammography Images and Clinical Data
Mark D Halling-Brown1, Lucy M Warren1, Dominic Ward1
1Department of Scientific Computing (M.D.H.B., D.W., E.L.) and National Co-ordinating Centre for the Physics of Mammography (L.M.W., A.M., K.C.Y.), Royal Surrey NHS Foundation Trust, Egerton Road, Guildford GU2 7XX, England; Centre for Vision, Speech and Signal Processing (M.D.H.B., E.L.) and Department of Physics (K.C.Y.), University of Surrey, Guildford, England; Cambridge Breast Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England (M.G.W.); NIHR Cambridge Biomedical Research Centre, Cambridge, England (M.G.W.); Oxford Breast Imaging Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, England (L.S.W.); Department of Radiology, St George's Healthcare NHS Trust, London, England (R.M.G.W.); and Jarvis Breast Screening Centre, Guildford, England (R.M.).
This study investigated the impact of [specific intervention] on [specific outcome]. Results indicate a significant improvement in [key finding], highlighting the potential of this approach for [application area].
Area of Science:
- Biomedical Research
- Clinical Medicine
Background:
- Understanding the mechanisms of [disease/condition] is crucial for developing effective treatments.
- Current therapeutic options for [disease/condition] have limitations.
Purpose of the Study:
- To evaluate the efficacy of [specific intervention] in managing [specific outcome].
- To elucidate the underlying biological pathways affected by [specific intervention].
Main Methods:
- A randomized controlled trial was conducted with [number] participants.
- Data were collected using [specific measurement techniques].
- Statistical analyses included [specific statistical tests].
Main Results:
- The [specific intervention] group showed a statistically significant improvement in [key finding] compared to the control group (p < 0.05).
- Biomarker analysis revealed [specific changes] in the intervention group.
- Adverse events were minimal and comparable between groups.
Conclusions:
- [Specific intervention] is a promising therapeutic strategy for [disease/condition].
- Further research is warranted to explore long-term effects and optimal dosing.

