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Updated: Nov 7, 2025

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
04:05

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Published on: August 22, 2025

256

Anastomotic Ulcers: A Tertiary Centre Experience of Endoscopic Management Techniques

Harriet Barraclough1, Ayesha Girach2, Prithviraj Rao3

  • 1Sheffield Children's Hospital, Western Bank, Sheffield.

Journal of Pediatric Gastroenterology and Nutrition
|May 3, 2021
PubMed

Insights

Anastomotic ulcers in children are rare but treatable. Endoscopic interventions, like argon plasma coagulation and clips, are effective for non-IBD patients not requiring transfusion.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Endoscopic Interventions

Background:

  • Neonatal care and surgical advances increase pediatric bowel anastomoses.
  • Anastomotic ulcers are a rare complication with unclear pathogenesis.
  • Limited effective treatment strategies and endoscopic experience exist for pediatric anastomotic ulcers.

Purpose of the Study:

  • To report a tertiary center's experience managing pediatric anastomotic ulcers.
  • To evaluate the efficacy of endoscopic techniques in managing these ulcers.

Main Methods:

  • Retrospective case series of nine pediatric anastomotic ulcer patients.
  • Management included medical therapy, endoscopic interventions (argon plasma coagulation, clips), and surgery.
  • Patients were categorized by inflammatory bowel disease (IBD) status and transfusion requirement.

Main Results:

  • Two IBD patients responded to optimized medical therapy.
  • Non-IBD patients requiring transfusion (n=2) needed surgery.
  • Non-IBD patients not requiring transfusion (n=4) responded to aminosalicylates (n=1) or endoscopic therapy (n=3).

Conclusions:

  • Endoscopic interventions are effective for pediatric anastomotic ulcers in non-IBD patients not requiring transfusion.
  • Transfusion requirement may indicate a need for surgical intervention.
  • Further research into optimal management strategies is warranted.

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