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The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
Published on: October 7, 2016
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Translational Applications of Hydrogels.
Santiago Correa1, Abigail K Grosskopf2, Hector Lopez Hernandez1
1Materials Science & Engineering, Stanford University, Stanford, California 94305, United States.
Chemical Reviews
|May 3, 2021
Summary
Hydrogel technology offers versatile solutions for drug delivery, tissue regeneration, and medical implants. Injectable hydrogels show particular promise for advanced biomedical and environmental applications.
Area of Science:
- Biomaterials Science
- Translational Medicine
- Environmental Engineering
Background:
- Hydrogels possess unique properties enabling diverse applications.
- These properties are crucial for drug/cell delivery, tissue regeneration, and medical implants.
- Applications extend beyond medicine to environmental engineering.
Purpose of the Study:
- To review major hydrogel capabilities, emphasizing injectable hydrogels.
- To explore translational applications in medicine and the environment.
- To highlight interdisciplinary collaboration in hydrogel development.
Main Methods:
- Review of current hydrogel technology and applications.
- Focus on injectable hydrogels and their benefits.
- Discussion of preclinical and clinical development, including mechanical scaling.
Main Results:
- Hydrogels offer solutions for cancer immunotherapy, tissue engineering, and vaccination.
- Injectable hydrogels present novel benefits for targeted therapies.
- Interdisciplinary efforts are key to advancing hydrogel functionalities.
Conclusions:
- Hydrogels have expansive potential for impactful differences across numerous fields.
- Continued research and collaboration will drive innovation in hydrogel technology.
- Mechanical design is critical for scaling injectable hydrogels for clinical use.

