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Published on: March 15, 2017
A new 8,3'-neolignan from Solanum procumbens Lour
Nhan Trung Nguyen1,2,3, Thuy Thanh Thi Tran1,2, Phu Hoang Dang1,2
1Faculty of Chemistry, University of Science, Ho Chi Minh City, Vietnam.
Abstract:
The phytochemical investigation of the EtOAc-soluble fraction of the aerial parts of Solanum procumbens Lour. has been carried out to obtain seven compounds, including a new 8,3'-neolignan named solacanin A (1). Their chemical structures were elucidated based on the spectroscopic data interpretation. All isolated compounds were tested for their α-glucosidase inhibitory activity. Compounds 1 and 3-6 showed inhibitory activity with IC50 values of 221.5, 18.9, 6.0, 104.1, and 219.7 µM, respectively.[Formula: see text].

