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Updated: Nov 7, 2025

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
Published on: July 1, 2020
Has GWAS lost its status as a paragon of open science?
Callie Burt1,2, Marcus Munafò3,4
1Department of Criminal Justice & Criminology, Georgia State University, Atlanta, United States of America.
Abstract:
Genomic research led the way in open science, a tradition continued by genome-wide association studies (GWAS)-through the sharing of materials, results, and data. Coordinated quality control procedures also contributed to robust findings. However, recent years have seen declines in GWAS transparency. Here, we assess some shifts away from open science practices with the aim of stimulating a discussion of these issues.
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