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Trileaflet Aortic Valve Reconstruction Using Bovine Pericardium.
Laichun Song1, Xiao Wang2, Chao Tao1
1Department of Cardiac Surgery, Asia Heart Hospital, Wuhan, P.R. China; Affiliated Wuhan University of Science and Technology, Wuhan, P.R. China.
Heart, Lung & Circulation
|May 4, 2021
Summary
Trileaflet aortic valve reconstruction using bovine pericardium shows promising mid- and long-term results for various aortic valve diseases. This durable procedure offers encouraging survival rates and low rates of reoperation.
Area of Science:
- Cardiovascular Surgery
- Biomaterials in Medicine
- Aortic Valve Disease Management
Background:
- Trileaflet aortic valve reconstruction is an established procedure for diverse aortic valve pathologies.
- Bovine pericardium is utilized for engineered leaflet creation.
Purpose of the Study:
- To evaluate the feasibility and long-term durability of trileaflet aortic valve reconstruction with bovine pericardium.
- To assess clinical outcomes in patients undergoing this reconstructive procedure.
Main Methods:
- A retrospective review of 519 patients who underwent trileaflet aortic valve reconstruction with bovine pericardium between April 2008 and December 2019.
- Patient data including demographics, aortic valve disease type, and follow-up outcomes were analyzed.
- Pericardial leaflet size was individually tailored to the aortic root dimensions.
Main Results:
- Successful reconstruction without intraoperative conversion to prosthetic valve replacement in all patients.
- Low in-hospital mortality (1.2%) and 10-year cumulative survival rate of 94.7%.
- Actuarial freedom from redo aortic valve surgery was 88.2% at 10 years, with encouraging hemodynamic results.
Conclusions:
- Trileaflet aortic valve reconstruction with bovine pericardium demonstrates encouraging mid- and long-term outcomes.
- Individualized sizing of engineered pericardial leaflets is crucial for successful reconstruction.
- The procedure is a viable option for patients with various aortic valve diseases.
