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Reducing Self-harm in Adolescents. An individual participant data meta-analysis (RISA-IPD): systematic review
Alexandra Wright-Hughes1, Rebecca Walwyn2, Judy M Wright3
1Complex Interventions Division, Clinical Trial Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK a.wright-hughes@leeds.ac.uk.
This study will identify which adolescents benefit most from self-harm interventions. It uses a systematic review and individual participant data meta-analysis to find effective treatments for subgroups of young people.
Area of Science:
- Psychiatry
- Clinical Psychology
- Adolescent Health
Background:
- Adolescent self-harm affects up to 10% annually, with high repetition rates and mortality.
- Evidence for effective interventions for adolescent self-harm is limited.
- Understanding treatment effectiveness for specific adolescent subgroups is crucial.
Purpose of the Study:
- To conduct a systematic review and individual participant data meta-analysis (IPD-MA).
- To identify adolescent subgroups that benefit from specific therapeutic interventions for self-harm.
- To inform research recommendations for effective self-harm treatments.
Main Methods:
- Systematic literature search of randomized controlled trials (RCTs) up to August 2019.
- Two-stage IPD-MA to evaluate intervention effectiveness on self-harm repetition and other outcomes.
- Subgroup analyses and meta-regression to identify moderators of treatment effects.
Main Results:
- This section will be populated upon study completion.
Conclusions:
- This section will be populated upon study completion.
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