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Updated: Nov 7, 2025

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Emergency amputation necessitated within 24 hours by a human bite: a case report.

Guozheng Zhu1, Canjun Zeng2,3,4, Song Yuan5

  • 1Division of Orthopaedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

The Journal of International Medical Research
|May 4, 2021
PubMed
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A severe Aeromonas hydrophila infection from a human bite led to gas gangrene-like changes and required emergency amputation. Early intervention is crucial, especially for immunocompromised patients.

Area of Science:

  • Infectious Diseases
  • Surgical Pathology
  • Clinical Medicine

Background:

  • Human bites can lead to severe infections, necessitating prompt medical evaluation and intervention.
  • Predisposing factors, such as myelodysplastic syndrome, can increase susceptibility to severe outcomes from infections.

Observation:

  • A 68-year-old male presented with rapid progression of infection, systemic poisoning, and gas gangrene-like changes following a child's human bite on the forearm.
  • Diagnostic workup included imaging (X-ray, ultrasound, CT), laboratory tests, and multidisciplinary consultation.
  • Bacteriological and pathological examinations identified Aeromonas hydrophila as the causative agent of extensive necrotizing fasciitis.

Findings:

  • Emergency open amputation was performed within 24 hours of the injury.
Keywords:
Aeromonas hydrophilaHuman biteamputationcase reportgas gangrenesevere necrotizing fasciitis

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  • Post-operative intensive care unit management included anti-infection and anti-shock treatments.
  • The patient recovered without further complications and was discharged.
  • Implications:

    • This case highlights the critical need for timely and aggressive treatment of human bite-related infections.
    • Aeromonas hydrophila is a significant pathogen capable of causing severe necrotizing fasciitis and systemic toxicity.
    • Identifying and managing underlying comorbidities is essential for improving patient outcomes in severe infection cases.