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Updated: Nov 6, 2025

Preparation and Immunostaining of Myelinating Organotypic Cerebellar Slice Cultures
Published on: March 20, 2019
Modeling myelin: A toolkit for exploring myelin's mysteries in vitro
Madeline H Cooper1, J Bradley Zuchero1
1Department of Neurosurgery, Stanford University, Stanford, CA, USA.
Abstract:
In the myelin field, there is a lack of reliable in vitro tools to study myelination, especially using human cells. In this issue of Developmental Cell, James et al. present a guide to generating human iPSC-derived "myelinoids"-3D models of myelination that reliably achieve mature myelin formation.
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