Can we determine recurrent epistaxis by hemogram parameters in children?
Nagehan Erdoğmuş Küçükcan1, Mahmut Alper Kanmaz2
1Adana Çukurova State Hospital, Otorhinolaryngology Department, Adana, Turkey.
Insights
Pediatric epistaxis (nosebleeds) may be linked to specific blood markers. This study found lower plateletcrit (PCT) and higher neutrophil-lymphocyte ratio (NLR) in children with nosebleeds, suggesting their diagnostic potential.
Area of Science:
- Pediatric Otolaryngology
- Hematology
Background:
- Epistaxis is a frequent cause for pediatric otolaryngology clinic visits.
- Diagnosis typically relies on clinical examination and laboratory tests.
Purpose of the Study:
- To evaluate simple blood parameters for diagnosing pediatric epistaxis.
- To assess the predictive value of neutrophil-lymphocyte ratio (NLR), eosinophil-LR (ELR), platelet-LR (PLR), plateletcrit (PCT), mean platelet volume (MPV), and platelet distribution width (PDW).
Main Methods:
- Retrospective analysis of 240 pediatric patients (120 epistaxis, 120 healthy controls) from 2018-2020.
- Comparison of various hemogram parameters and platelet indices between groups.
Main Results:
- No significant associations found for MPV, PDW, PLR, and ELR.
- Significant differences observed in PCT and NLR.
- Children with epistaxis had lower average PCT (p=0.022) and higher average NLR (p=0.004) compared to controls.
Conclusions:
- PCT has not been previously investigated in relation to epistaxis.
- This study is the first to suggest a relationship between PCT values and pediatric epistaxis.
- PCT and NLR may serve as useful diagnostic markers for pediatric epistaxis.
Objective:
Epistaxis in children is a common reason for admission at otolaryngology outpatient clinics. Patients are diagnosed by clinical examination and laboratory tests. We aimed to evaluate epistaxis using simple blood parameters useful for diagnosis.
Material And Methods:
This study includes a retrospective analysis of 240 patients, including 120 study group and 120 healthy pediatric patients, who applied to the ENT outpatient clinic with the diagnosis of epistaxis between 2018 and 2020. This study is designed to analyze the predictive values of neutrophil-lymphocyte ratio (NLR), eosinophil-LR (ELR), platelet-LR (PLR), plateletcrit (PCT), mean platelet volume (MPV), and platelet distribution width (PDW) in pediatric epistaxis.
Results:
Serological factors were assessed and no statistical associations in MPV, PDW, PLR, and ELR values were found. However, significant changes were found for PCT and NLR within the patient and control groups. The average PCT was lower in the study group in comparison to the controls (p = 0.022). The average NLR was higher in the study group in comparison to the controls (p = 0.004).
Conclusion:
The examination of children with epistaxis, as well as their management, following admission to the outpatient clinic continues to evolve. Although many studies have investigated the hemogram parameters and platelet indices, the PCT value has never been investigated in epistaxis. To our knowledge, our study is the first to demonstrate a relationship to PCT values and epistaxis.
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