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Updated: Nov 6, 2025

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Late-Onset Mirror Syndrome.

Erinna Mohamad Zon1, Nik Ahmad Zuky Nik Lah2, Pek Sung Hoo3

  • 1MD (USM), MMed O&G (USM), Department of Obstetrics & Gynaecology, School of Medical Sciences, Universiti Sains Malaysia, Malaysia, Department of Obstetrics & Gynaecology, Hospital Universiti Sains Malaysia, Malaysia

Malaysian Family Physician : the Official Journal of the Academy of Family Physicians of Malaysia
|May 5, 2021
PubMed
Summary

Mirror syndrome, a rare pregnancy complication, involves fetal hydrops, placental edema, and maternal edema. Early recognition is crucial to prevent severe maternal and fetal outcomes.

Keywords:
Ballantyne syndromeMirror syndromehydrops fetalis

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Perinatology

Background:

  • Mirror syndrome is a rare pregnancy complication.
  • It is characterized by fetal hydrops, placental edema, and maternal edema.
  • This condition is associated with high fetal mortality and maternal morbidity.

Observation:

  • A case of late-onset Mirror syndrome presented at 36 weeks gestation.
  • The patient exhibited excessive weight gain and signs mimicking preeclampsia.
  • This presentation highlights diagnostic challenges in late-gestation pregnancies.

Findings:

  • Mirror syndrome involves a triad of fetal hydrops, placental edema, and maternal edema.
  • Late-onset presentation can mimic other conditions like preeclampsia.
  • Delayed diagnosis significantly increases risks.

Implications:

  • Increased awareness of Mirror syndrome is vital for timely diagnosis and treatment.
  • Prompt management can mitigate severe maternal and perinatal morbidity and mortality.
  • This case underscores the importance of considering rare diagnoses in complex obstetric presentations.