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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

119
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
119
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

79
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
79
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

73
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
73
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

128
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
128
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

114
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

244
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
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Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
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Endocarditis caused by Thalassospira sp.

Laurène Deconinck1, Rémi Gschwind2, Marie Petitjean2

  • 1AP-HP, Hôpital Bichat, Service de Maladies Infectieuses et Tropicales, F-75018 Paris, France.

Idcases
|May 5, 2021
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Summary

A rare case of infective endocarditis caused by Thalassospira bacteria was identified in a French Polynesian fisherman. DNA sequencing confirmed the pathogen, highlighting its role in valvular heart disease.

Keywords:
Infective endocarditisNanopore sequencingNext-Generation SequencingThalassospira

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Cardiology

Background:

  • Infective endocarditis (IE) is a serious infection of the heart valves.
  • Valvular heart disease increases susceptibility to IE.
  • Geographic location and occupation can influence exposure to specific pathogens.

Observation:

  • A 53-year-old fisherman from French Polynesia presented with symptoms suggestive of IE.
  • The patient had a history of pre-existing valvular lesions.
  • A rare bacterial species, Thalassospira sp., was implicated in the infection.

Findings:

  • DNA sequencing successfully identified the causative agent as Thalassospira sp.
  • Mass spectrometry methods were unable to identify the bacterium.
  • This case represents a novel association between Thalassospira sp. and infective endocarditis.

Implications:

  • Highlights the importance of advanced molecular techniques like DNA sequencing for pathogen identification in complex cases.
  • Suggests Thalassospira sp. as a potential etiological agent for infective endocarditis, particularly in specific geographic and occupational settings.
  • Warrants further investigation into the prevalence and pathogenicity of Thalassospira species in human infections.