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Imipramine and social-vocational adjustment in chronic depression
J H Kocsis1, A J Frances, C Voss
1Department of Psychiatry, Payne Whitney Psychiatric Clinic, New York Hospital--Cornell Medical Center 10021.
The American Journal of Psychiatry
|August 1, 1988
Abstract:
The authors compared the effects of 6 weeks of imipramine treatment with 6 weeks of placebo treatment on social and vocational impairment in chronic depression. Imipramine was associated with significantly greater pre- to posttreatment improvement of social-vocational impairments in chronic depression, suggesting that these impairments may have represented affective symptoms rather than characterologic deficits.