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Updated: Nov 6, 2025

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
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Serum potassium levels and prognosis in HBV-associated decompensated cirrhosis

JianJiang Huang1, Ming Cai2, Xia He2

  • 1Department of Critical Care Medicine, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.

Journal of Clinical Laboratory Analysis
|May 5, 2021
PubMed

Insights

Serum potassium levels are a key predictor of outcomes in patients with Hepatitis B virus-related decompensated cirrhosis (HBV-DeCi). Monitoring potassium can help assess prognosis and improve patient care for this liver condition.

Area of Science:

  • Hepatology
  • Internal Medicine
  • Clinical Research

Background:

  • Serum potassium disorders are common in advanced cirrhosis, impacting patient outcomes.
  • The specific role of serum potassium in Hepatitis B virus-related decompensated cirrhosis (HBV-DeCi) requires further elucidation.

Purpose of the Study:

  • To evaluate the impact of serum potassium levels on clinical outcomes in patients with HBV-DeCi.
  • To identify serum potassium as a potential prognostic factor in HBV-DeCi.

Main Methods:

  • Retrospective study involving 155 patients diagnosed with HBV-DeCi.
  • Multivariate analysis was employed to identify independent prognostic factors.
  • Receiver operating characteristic (ROC) curves were utilized to assess the predictive accuracy of mortality.

Main Results:

  • The 30-day in-hospital mortality rate was 12.9%.
  • Significant differences in serum potassium levels were observed between survivors and non-survivors.
  • Both Model for End-Stage Liver Disease (MELD) score and serum potassium level were identified as independent predictors of outcomes.
  • Combining MELD score and serum potassium improved prognostic accuracy.

Conclusions:

  • Serum potassium serves as an effective predictor of adverse outcomes in patients with HBV-DeCi.
  • Serum potassium monitoring can aid in risk stratification and management of HBV-DeCi patients.
Abstract

Keywords:
decompensated cirrhosismortalityprognostic factorsserum potassium

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