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The Association of Spondylitis and Aortic Aneurysm Disease

Nikolaos Patelis1, Petroula Nana2, Konstantinos Spanos2

  • 13rd Department of Vascular Surgery, Athens Medical Center, Marousi, Greece.

Annals of Vascular Surgery
|May 5, 2021
PubMed

Insights

This study suggests spondylitis and aortic aneurysms may share causes, often affecting lumbar vertebrae. More research is needed to confirm links and guide treatment for these related conditions.

Area of Science:

  • Medical research
  • Clinical studies
  • Literature review

Background:

  • Spondylitis and aortic aneurysms are distinct conditions.
  • Potential shared etiopathology between spondylitis and aortic aneurysms is not well-defined.

Purpose of the Study:

  • To investigate the relationship between spondylitis and aortic aneurysmal disease.
  • To review existing literature on co-occurring spondylitis and aortic aneurysms.

Main Methods:

  • Systematic literature search of MEDLINE, EMBASE, and CENTRAL databases up to May 2019.
  • Inclusion of articles reporting on patients with both spondylitis and aortic aneurysm.

Main Results:

  • The infrarenal aorta (56.9%) and lumbar vertebrae (79.7%) were most commonly affected.
  • Common symptoms included back pain (79.1%), fever (33.7%), and lower limb pain (29.1%).
  • Infectious causes were identified in 25.1% of cases; 30-day mortality was 8.1%.

Conclusions:

  • Synchronous spondylitis and aortic aneurysm may share infectious or inflammatory etiopathologies.
  • The lumbar spine is frequently involved in these co-occurring conditions.
  • Limited data quality prevents definitive conclusions on optimal treatment strategies.
Abstract

Keywords:
AneurysmAortaEtiopathologyInflammationSpondylitis

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