Related Experiment Videos
[Value of cyclosporin A in dermatomyositis in a child]
P Reinert1, C Hamberger, M C Rahimy
1Service de Pédiatrie, Laboratoire Hospitalo-Universitaire de Pharmacologie, Centre Hospitalier Intercommunal, Créteil.
Archives Francaises De Pediatrie
|March 1, 1988
Abstract:
Cyclosporin A was used in a 3 1/2 year-old child with dermatomyositis exhibiting severe junctional impairment and intolerance to steroids. After a few weeks, marked clinical improvement was observed allowing a reduction of the doses of steroids. After 9 months, the clinical status was satisfactory: the calcifications had lost their inflammatory characteristics. No side effect of cyclosporin A was observed at the dose used (4.4 mg/kg/d) which maintained effective blood concentrations between 80 and 220 ng/ml.