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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Updated: Nov 6, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
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A New Rash Differential: CoVID-19.

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  • 1Vanderbilt University, Nashville, Tennessee; Middle Tennessee School of Anesthesia, Madison, Tennessee; Vanderbilt University Medical Center, Nashville, Tennessee; and TeamHealth, Columbia, Tennessee.

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Summary

COVID-19 can cause various skin rashes beyond respiratory symptoms. Emergency nurse practitioners should recognize these dermatological signs for early COVID-19 diagnosis and to limit virus spread.

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Area of Science:

  • Dermatology
  • Emergency Medicine
  • Infectious Diseases

Background:

  • The COVID-19 pandemic has significantly affected healthcare, particularly emergency medicine.
  • While respiratory symptoms are common, non-respiratory manifestations of COVID-19 are increasingly recognized.

Observation:

  • Dermatological findings associated with COVID-19 include maculopapular and urticarial rashes.
  • Other reported skin changes encompass chilblain-like lesions, livedo reticularis, vesicular, and petechial rashes.

Findings:

  • Emergency nurse practitioners must be aware of diverse COVID-19 presentations, including cutaneous manifestations.
  • Recognizing these skin findings can aid in identifying potentially asymptomatic or mildly symptomatic infected individuals.

Implications:

  • Early identification of COVID-19 through dermatological signs can lead to prompt diagnosis.
  • This recognition may help mitigate the further transmission of SARS-CoV-2.