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Negative pressure wound therapy does not decrease postoperative wound complications in patients undergoing mastectomy

L De Rooij1, S M J van Kuijk2, E R M van Haaren3

  • 1Department of Surgery, Zuyderland Medical Center, Postbus 5500, 6130 MB, Sittard, The Netherlands. l.derooij@zuyderland.nl.

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|May 6, 2021
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Summary
This summary is machine-generated.

Negative pressure wound therapy (NPWT) did not reduce wound complications after mastectomy. This study found no significant difference in complications or seroma development between NPWT and standard care for closed mastectomy incisions.

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Area of Science:

  • Surgical Oncology
  • Wound Healing
  • Medical Devices

Background:

  • Mastectomy patients face high rates of wound complications.
  • Negative pressure wound therapy (NPWT) shows promise for closed surgical incisions.
  • Limited data exists on NPWT for closed mastectomy incisions.

Purpose of the Study:

  • To evaluate the efficacy of NPWT in reducing postoperative complications after mastectomy.
  • To compare wound complication rates between NPWT and conventional care in mastectomy patients.

Main Methods:

  • Prospective study of 50 mastectomy patients treated with NPWT for seven days post-surgery.
  • Comparison with a historical control group (111 patients) from a randomized controlled trial.
  • Primary outcome: postoperative wound complications (infection, necrosis, dehiscence) within three months.

Main Results:

  • Wound complication rates were 28% in the NPWT group versus 18.9% in the control group (OR=1.67).
  • No statistically significant difference in unplanned hospital visits or clinically significant seroma (CSS) development.
  • NPWT did not demonstrate a benefit in reducing complications for closed mastectomy incisions.

Conclusions:

  • Avelle negative pressure wound therapy does not decrease postoperative wound complications after mastectomy.
  • NPWT offers no significant advantage over standard care for preventing complications or seromas in closed mastectomy wounds.