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Risk Management on Pre-Exposure Prophylaxis Adherence of Men Who Have Sex with Multiple Men: A Multicenter
Jiaxiu Liu1,2, Ruibin Deng1, Bing Lin1
1School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Risk Management and Healthcare Policy
|May 6, 2021
Summary
Pre-exposure prophylaxis (PrEP) adherence is crucial for HIV prevention in men who have sex with multiple men (MSMM). On-demand PrEP medication and improved threat perception enhance adherence, while targeting students and those with poor HIV knowledge is key for prevention strategies.
Area of Science:
- Public Health
- Epidemiology
- Behavioral Science
Background:
- Men who have sex with multiple men (MSMM) are at high risk for HIV infection.
- Pre-exposure prophylaxis (PrEP) is an effective HIV prevention method.
- Limited research exists on PrEP adherence among MSMM in China.
Purpose of the Study:
- To explore factors influencing PrEP adherence in HIV-negative MSMM in Western China.
- To apply Rogers' Protective Motivation Theory (PMT) to understand adherence.
- To inform future HIV prevention and risk management strategies.
Main Methods:
- A 2-year follow-up cohort study involving MSMM in China.
- Application of Protective Motivation Theory (PMT) to assess adherence factors.
- Logistic regression analysis to identify predictors of PrEP adherence.
Main Results:
- 496 MSMM were analyzed; 60.28% showed good adherence.
- Poor adherence was linked to on-demand PrEP use, being a student, occasional condom use, and good HIV knowledge.
- Higher threat perception correlated with higher susceptibility; lower response cost increased protective motivation.
Conclusions:
- On-demand PrEP medication use is associated with better adherence.
- Preventive interventions should target students, occasional condom users, and individuals with poor HIV knowledge.
- Enhancing threat perception and reducing response costs can improve PrEP adherence for MSMM.
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