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Risk Management on Pre-Exposure Prophylaxis Adherence of Men Who Have Sex with Multiple Men: A Multicenter

Jiaxiu Liu1,2, Ruibin Deng1, Bing Lin1

  • 1School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.

Risk Management and Healthcare Policy
|May 6, 2021
PubMed
Abstract

Insights

Pre-exposure prophylaxis (PrEP) adherence is crucial for HIV prevention in men who have sex with multiple men (MSMM). On-demand PrEP medication and improved threat perception enhance adherence, while targeting students and those with poor HIV knowledge is key for prevention strategies.

Area of Science:

  • Public Health
  • Epidemiology
  • Behavioral Science

Background:

  • Men who have sex with multiple men (MSMM) are at high risk for HIV infection.
  • Pre-exposure prophylaxis (PrEP) is an effective HIV prevention method.
  • Limited research exists on PrEP adherence among MSMM in China.

Purpose of the Study:

  • To explore factors influencing PrEP adherence in HIV-negative MSMM in Western China.
  • To apply Rogers' Protective Motivation Theory (PMT) to understand adherence.
  • To inform future HIV prevention and risk management strategies.

Main Methods:

  • A 2-year follow-up cohort study involving MSMM in China.
  • Application of Protective Motivation Theory (PMT) to assess adherence factors.
  • Logistic regression analysis to identify predictors of PrEP adherence.

Main Results:

  • 496 MSMM were analyzed; 60.28% showed good adherence.
  • Poor adherence was linked to on-demand PrEP use, being a student, occasional condom use, and good HIV knowledge.
  • Higher threat perception correlated with higher susceptibility; lower response cost increased protective motivation.

Conclusions:

  • On-demand PrEP medication use is associated with better adherence.
  • Preventive interventions should target students, occasional condom users, and individuals with poor HIV knowledge.
  • Enhancing threat perception and reducing response costs can improve PrEP adherence for MSMM.
Keywords:
MSMPrEPWestern Chinaadherencemultiple sexual partnersprotective motivation theory

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