A manifesto for reproducible science.

Area of Science:

• Scientific research methodology
• Publication ethics
• Research integrity

Background:

• Published scientific literature faces challenges in reliability and efficiency.
• This impacts the credibility of research findings and the pace of scientific discovery.
• Optimizing key elements of the scientific process is crucial.

Purpose of the Study:

• To advocate for measures that enhance the reliability and efficiency of scientific research.
• To identify key areas within the scientific process for optimization.
• To facilitate action towards improving scientific transparency and reproducibility.

Main Methods:

• Focus on optimizing methods, reporting and dissemination, reproducibility, evaluation, and incentives.
• Reviewing evidence from simulations and empirical studies on proposed measures.
• Discussing the goals and implementation strategies for these measures.

Main Results:

• Evidence suggests proposed measures can likely improve research reliability and efficiency.
• Broad adoption necessitates iterative evaluation and improvement by stakeholders.
• Implementation requires coordinated efforts from researchers, institutions, funders, and journals.

Conclusions:

• Adopting proposed measures can significantly improve the transparency, reproducibility, and efficiency of scientific research.
• Iterative evaluation and improvement are essential for widespread adoption.
• This work aims to facilitate concrete actions toward a more robust scientific process.