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Related Concept Videos

Antipsychotic Drugs: Therapeutic Uses and Side Effects01:21

Antipsychotic Drugs: Therapeutic Uses and Side Effects

468
Antipsychotic drugs primarily block dopamine and serotonin receptors and cholinergic, adrenergic, and histaminergic receptors, thereby reducing hallucinations and delusions in conditions like schizophrenia. However, they can trigger unwanted extrapyramidal effects such as dystonias, Parkinson-like symptoms, and tardive dyskinesia.
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
468
Drug Therapy01:28

Drug Therapy

135
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
135
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
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Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

302
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
302
Antipsychotic Drugs: Typical and Atypical Agents01:21

Antipsychotic Drugs: Typical and Atypical Agents

471
Antipsychotic drugs are classified into first-generation (typical) drugs including phenothiazines; and second-generation (atypical) drugs. Chlorpromazine hydrochloride (Thorazine), a phenothiazine derivative, broadly impacts the central, autonomic, and endocrine systems. This drug, along with typical agents like haloperidol (Haldol), primarily works by antagonizing D2 receptors, thus reducing dopaminergic neurotransmission. However, typical antipsychotics can cause side effects such as sedation...
471
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

403
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
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Development of a Virtual Reality Assessment of Everyday Living Skills
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Atypical antipsychotics: Managing adverse effects.

Brayden Kameg1, Claire Champion1

  • 1Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, Pennsylvania, USA.

Perspectives in Psychiatric Care
|May 6, 2021
PubMed
Summary
This summary is machine-generated.

Atypical antipsychotics are widely used but can cause adverse effects like metabolic syndrome. Early identification and management strategies are key to improving patient quality of life.

Keywords:
atypical antipsychoticsextrapyramidal symptomstardive dyskinesia

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Area of Science:

  • Pharmacology
  • Clinical Medicine
  • Psychiatry

Background:

  • Atypical antipsychotics are frequently prescribed for various psychiatric conditions.
  • Their efficacy is well-established, but they are linked to significant adverse effects.
  • Understanding these risks is crucial for patient safety and treatment adherence.

Purpose of the Study:

  • To present a comprehensive overview of common adverse effects associated with atypical antipsychotic medications.
  • To outline effective management strategies for mitigating these adverse effects.
  • To emphasize the importance of patient-centered care in managing atypical antipsychotic therapy.

Main Methods:

  • Literature review of common adverse effects.
  • Synthesis of current management guidelines.
  • Discussion of clinical implications for healthcare providers.

Main Results:

  • Common adverse effects include metabolic syndrome (weight gain, dyslipidemia, hyperglycemia), extrapyramidal symptoms (EPS), and tardive dyskinesia (TD).
  • Other potential adverse effects encompass sedation, cardiovascular effects, and endocrine changes.
  • Management involves proactive monitoring, dose adjustment, lifestyle interventions, and switching medications when necessary.

Conclusions:

  • Atypical antipsychotics, while effective, necessitate vigilant monitoring for adverse effects.
  • Implementing targeted management strategies can significantly reduce the incidence and severity of adverse events.
  • Establishing a supportive therapeutic alliance with patients and caregivers is paramount for successful management and improved quality of life.