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Annual Screening Mammography Associated With Lower Stage Breast Cancer Compared With Biennial Screening
Sarah E H Moorman1, Akshat C Pujara1,2, Michelle D Sakala1
1Department of Radiology, Division of Breast Imaging, Breast Care Center, University of Michigan Rogel Cancer Center, Ann Arbor, MI.
AJR. American Journal of Roentgenology
|May 6, 2021
Summary
Annual mammographic screening detects breast cancer at earlier stages and reduces interval cancers compared to biennial or nonannual screening. This approach leads to better outcomes for women
Area of Science:
- Oncology
- Radiology
- Public Health
Background:
- Screening mammography is crucial for early breast cancer detection.
- The optimal frequency of mammographic screening remains an area of research.
- Comparing annual versus nonannual screening can impact patient outcomes.
Purpose of the Study:
- To compare breast cancer characteristics and treatment regimens.
- To evaluate differences between annual and nonannual screening mammography cohorts.
Main Methods:
- Retrospective cohort study of 490 patients diagnosed with breast cancer (2016-2017).
- Comparison of annual, biennial, and triennial mammography screening frequencies.
- Statistical analysis using t tests, Wilcoxon rank sum tests, chi-square, and Fisher exact tests.
Main Results:
- Annual screening was associated with fewer late-stage presentations (AJCC stage II-IV: 24.0% vs. 43.8%-44.4%).
- Annual screening significantly reduced interval cancers (10.5% vs. 33.3%-37.5%).
- Smaller mean tumor diameter was observed in the annual screening group (1.4 cm vs. 1.8 cm).
Conclusions:
- Annual mammographic screening is linked to lower breast cancer stage at diagnosis.
- Annual screening demonstrates a reduction in interval cancers compared to less frequent screening.
- These findings support the efficacy of annual screening for early breast cancer detection.
