Future stroke risk in the chronic phase of post-percutaneous coronary intervention

Shinsuke Muraoka1, Daiki Somiya1, Aoi Ebata1

  • 1Department of Neurosurgery, Tosei General Hospital, Aichi, Japan.

Plos One
|May 6, 2021
PubMed

Insights

Cerebrovascular events (CVEs) like stroke occur in 11.7% of patients after percutaneous coronary intervention (PCI). Coronary artery calcification (CAC) sites can predict future CVEs risk after PCI.

Area of Science:

  • Cardiology
  • Neurology
  • Radiology

Background:

  • Percutaneous coronary intervention (PCI) is a common procedure for coronary syndromes.
  • Stroke is a significant complication during PCI, but its incidence in the chronic phase is not well understood.

Purpose of the Study:

  • To investigate the prevalence of cerebrovascular events (CVEs) after PCI in the chronic phase.
  • To evaluate a simple coronary artery calcification (CAC) scoring method for predicting future CVEs.

Main Methods:

  • Prospective observational study of 171 patients who underwent PCI.
  • Follow-up for a median of 33 months to record cerebral infarction onset.
  • Analysis of coronary artery calcification (CAC) and cervical internal carotid artery stenosis.

Main Results:

  • Cerebral infarction occurred in 11.7% of patients.
  • Increased CAC sites (p=0.009) and post-PCI status for chronic coronary syndrome (p=0.049) were associated with CVEs.
  • A CAC site cutoff of 4.5 predicted future CVEs.

Conclusions:

  • A simple CAC evaluation method can predict future CVEs risk after PCI.
  • This method may be clinically applicable for risk stratification in patients undergoing PCI.

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