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Updated: Nov 6, 2025

Identification of Circular RNAs using RNA Sequencing
Published on: November 14, 2019
The Emerging Role of Circular RNAs in Cerebral Vascular Disorders
1Department of Neurology, Shengjing Hospital of China Medical University, Shenyang, China.
Background:
Circular RNAs (circRNAs) are covalently closed circular noncoding RNAs that are expressed in various life forms. CircRNAs have many characteristics, such as structural stability and tissue-specific expression that contribute to their role as a microRNA (sponge in gene regulation.
Summary:
Recent evidence suggests that circRNAs play an important role in the pathogenesis of cerebrovascular diseases (CVDs); however, the exact mechanism remains controversial. CircRNAs that are related to CVDs have great clinical significance. Key Messages: The present review provides an overview of the general biology of circRNAs, their relevant regulatory mechanisms, and their role in the pathophysiology of CVDs.
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