Validation of the 2019 Expert Consensus Algorithm for the Management of Conduction Disturbances After TAVR
Daniel Malebranche1, Joanna Bartkowiak2, Christoph Ryffel2
1Department of Cardiology, Inselspital, University of Bern, Bern, Switzerland; Dalhousie University and Queen Elizabeth II Health Sciences Centre and NS Health Authority, Halifax, Nova Scotia, Canada.
Insights
The 2019 consensus algorithm effectively identifies low-risk patients for early discharge after transcatheter aortic valve replacement (TAVR). However, it is less precise in identifying high-risk patients needing pacemakers.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Electrophysiology
Background:
- Optimal management of conduction disturbances post-TAVR remains unclear.
- A 2019 expert consensus algorithm was developed to guide management.
- This study validates the algorithm in a contemporary TAVR cohort.
Purpose of the Study:
- To validate the 2019 consensus algorithm for predicting pacemaker needs post-TAVR.
- To assess the algorithm's accuracy in stratifying patients for early discharge versus higher risk of heart block.
Main Methods:
- Retrospective analysis of a prospective registry of 1,439 TAVR patients (Jan 2014 - Dec 2019).
- Patients classified using the 2019 algorithm: early discharge, higher risk for heart block, or need for pacemaker.
- Primary endpoint: 30-day pacemaker implantation for high-degree atrioventricular block or complete heart block.
Main Results:
- The algorithm classified 73% for early discharge, 21% at higher risk, and 6% needing a pacemaker.
- 16% of patients (234/1,439) received a pacemaker within 30 days.
- Pacemaker rates: 2.7% (early discharge), 41% (higher risk), 100% (pacemaker group).
Conclusions:
- The 2019 algorithm safely identifies low-risk TAVR patients eligible for early discharge.
- It enables uniform management and facilitates early discharge for ~73% of patients.
- The algorithm demonstrates lower precision in identifying high-risk patients requiring pacemakers.
Objectives:
The aim of this study was to validate the 2019 consensus algorithm in a large cohort of contemporary transcatheter aortic valve replacement (TAVR) patients.
Background:
The optimal management of patients with atrioventricular conduction disturbances after TAVR is unknown. Guidance was consolidated in an expert consensus algorithm in 2019.
Methods:
In a retrospective analysis of a prospective registry, patients were classified according to the 2019 consensus algorithm as eligible for early discharge (day 1 or 2 after TAVR), higher risk for high-degree atrioventricular block (HAVB) or complete heart block (CHB) or in need for a permanent pacemaker (PPM). The primary endpoint was the incidence of PPM implantation for HAVB or CHB within 30 days after TAVR. Patients with prior PPM or implantable cardioverter-defibrillator implantation, valve-in-valve procedures, or incomplete electrocardiographic data were excluded.
Results:
Among 1,439 patients undergoing TAVR between January 2014 and December 2019, the 2019 consensus algorithm classified 73% as eligible for early discharge, 21% as at higher risk for HAVB or CHB, and 6% as in need of PPM. PPM implantation for HAVB or CHB occurred in 234 patients (16%) within 30 days after TAVR. The incidence of PPM implantation was 2.7% in the early discharge group, 41% in the group with higher risk for HAVB or CHB, and 100% in the PPM group.
Conclusions:
The 2019 consensus algorithm safely identifies patients with no need for PPM implantation. This strategy allows more uniform management of TAVR patients and facilitates early discharge of low-risk patients without prolonged monitoring in 3 of 4 patients. However, the algorithm is less precise in the identification of high-risk patients.
Related Concept Videos
Dysrhythmias VI: Management of Dysrhythmias
Mitral Stenosis III: Medical Management
Aortic Regurgitation III: Medical Management
Mitral Regurgitation III: Medical Management
Cardiac Catheterization IV: Nursing Management
Dysrhythmias II: Classification of Tachyarrhythmias


