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Bibliography of published COVID-19 in children literature

Philippa Anna Stilwell1, Alasdair P S Munro2,3, Emre Basatemur4

  • 1Department of Community Paediatrics, Evelina London Children's Hospital, London, UK.

Archives of Disease in Childhood
|May 7, 2021
PubMed

Insights

Early COVID-19 research in children showed a publication surge, but many studies were small case reports. This highlights the need for cautious interpretation of pediatric COVID-19 findings during the pandemic.

Area of Science:

  • Pediatric Infectious Diseases
  • Epidemiology
  • Bibliometrics

Background:

  • The COVID-19 pandemic presented a significant global health challenge.
  • Understanding the role of children in SARS-CoV-2 transmission and the clinical impact of infection on pediatric populations is crucial.
  • This study analyzes publication trends in pediatric COVID-19 literature during the initial six months of the pandemic.

Purpose of the Study:

  • To describe the publication trends of scientific literature concerning COVID-19 in children.
  • To analyze the characteristics of research published on pediatric COVID-19 in the early pandemic period.

Main Methods:

  • A comprehensive search of preprint and published literature was conducted across four major databases (PubMed, Scopus, Ovid-Embase, MedRXiv) from January 1 to June 30, 2020.
  • Titles and abstracts were screened using predefined inclusion and exclusion criteria.
  • Bibliometric analysis was performed on the selected literature.

Main Results:

  • A total of 476 relevant papers were identified out of 45,453 retrieved articles.
  • These publications described a cumulative total of up to 41,396 children, with a median of 6 children per paper.
  • Nearly 60% of the papers reported on 9 or fewer children, and half of the publications originated from Asia.

Conclusions:

  • The number of pediatric COVID-19 publications increased steadily during the study period, reflecting evolving understanding and policy.
  • A significant proportion of early research consisted of individual case reports or small case series, potentially limiting their contribution to advancing knowledge.
  • Findings underscore the importance of cautious interpretation of early pandemic literature and continuous review of clinical/policy decisions based on emerging evidence.
Abstract

Keywords:
COVID-19data collectionepidemiology

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