Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Global Health Perspective on the 2026 AHA/ASA Stroke Guidelines: Lessons from the Indian Health System.

Cerebrovascular diseases (Basel, Switzerland)·2026
Same author

Strategies to reduce osmotic stress during cryopreservation of red blood cells when using trehalose.

Scientific reports·2026
Same author

Preoperative stress markers as predictors of postoperative neuropsychological disorders in cardiac surgery patients: protocol for a single-centre prospective observational study (CAVALIR).

BMJ open·2026
Same author

Fiberoptic endoscopic evaluation of swallowing in German stroke units: a retrospective diagnosis-related group analysis (2019-2024).

Neurological research and practice·2026
Same author

Covert macrovascular disease and early outcome after ischemic cerebrovascular events.

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Imaging patterns of glioblastoma progression: Comparative analysis of sequential proton boost versus conventional photon therapy.

Neuro-oncology advances·2026

Related Experiment Video

Updated: Nov 6, 2025

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
04:55

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice

Published on: May 11, 2022

4.3K

Case Report: A Well-Hidden Cause for Myelopathy.

Tobias Braun1, Eva Schulz1,2, Maxime Viard1

  • 1Department of Neurology, University Hospital Giessen and Marburg, Giessen, Germany.

Frontiers in Neurology
|May 7, 2021
PubMed
Summary

Neurosarcoidosis, a rare neurological manifestation of sarcoidosis, can present with spinal cord syndrome due to bone marrow involvement. Early diagnosis via bone marrow biopsy is crucial for patients with unexplained neurological deficits.

Keywords:
bone marrow sarcoidosiscase reportmyelopathyneurosarcoidosisspinal cord syndrome

More Related Videos

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
09:29

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

11.7K
Implanting Glass Spinal Cord Windows in Adult Mice with Experimental Autoimmune Encephalomyelitis
09:20

Implanting Glass Spinal Cord Windows in Adult Mice with Experimental Autoimmune Encephalomyelitis

Published on: December 21, 2013

7.7K

Related Experiment Videos

Last Updated: Nov 6, 2025

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
04:55

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice

Published on: May 11, 2022

4.3K
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
09:29

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

11.7K
Implanting Glass Spinal Cord Windows in Adult Mice with Experimental Autoimmune Encephalomyelitis
09:20

Implanting Glass Spinal Cord Windows in Adult Mice with Experimental Autoimmune Encephalomyelitis

Published on: December 21, 2013

7.7K

Area of Science:

  • Neurology
  • Rheumatology
  • Hematology

Background:

  • Sarcoidosis is a systemic inflammatory disease affecting multiple organs.
  • Neurosarcoidosis occurs in <10% of patients, presenting diverse neurological symptoms.
  • Bone marrow involvement in sarcoidosis is rare but can lead to significant complications.

Observation:

  • A patient presented with progressive paraparesis and thoracic myelopathy of unknown origin.
  • Initial diagnostics and steroid treatment were insufficient.
  • Persistent leukopenia prompted a bone marrow biopsy, revealing sarcoidosis.

Findings:

  • The bone marrow sarcoidosis was identified as the cause of the patient's myelopathy and spinal cord syndrome.
  • Myocardial involvement was also detected.
  • Treatment with prednisolone and methotrexate led to symptom improvement, though residual spastic paresis remains.

Implications:

  • Neurosarcoidosis should be considered in cases of unexplained neurological deficits.
  • Bone marrow sarcoidosis can be an easily overlooked cause of myelopathy.
  • Abnormal blood counts warrant consideration of bone marrow biopsy for diagnosing neurosarcoidosis.