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Translocation t(11;21)(q24;q11.2) is a new nonrandomly occurring chromosome change in myelodysplastic syndromes
G Rege-Cambrin1, C Mecucci, S Kerim
1Dipartimento di Scienze biomediche e Oncologia Umana, University of Torino, Italy.
Cancer Genetics and Cytogenetics
|August 1, 1988
Abstract:
An identical translocation, t(11;21)(q24;q11.2), has been observed in three patients with a myelodysplastic syndrome. In all cases, duplication of the 11q+ marker and loss of the normal chromosome 11 were observed either at diagnosis or during the evolution of the disease. This apparently characteristic chromosome abnormality has not been previously described.