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Published on: April 23, 2021
Performances on the Montreal Cognitive Assessment Along the Cardiovascular Disease Continuum
Christine Gagnon1, Kathia Saillant1,2, Miloudza Olmand1,3
1Preventive Medicine and Physical Activity Centre and Research Center, Montreal Heart Institute, Montreal, Canada.
Insights
The Montreal Cognitive Assessment (MoCA) detects cognitive impairment in later stages of cardiovascular disease, like heart failure, particularly in verbal fluency and memory. Earlier detection may need more detailed neuropsychological testing.
Area of Science:
- Cardiology
- Neurology
- Cognitive Science
Background:
- Cardiovascular diseases (CVD) encompass a spectrum from risk factors to heart failure, often accompanied by cognitive impairment (CI).
- Cognitive impairment is prevalent in CVD, affecting up to 50% of heart failure patients and linked to adverse outcomes.
- Early CI detection in CVD is crucial, with the Montreal Cognitive Assessment (MoCA) being a common screening tool.
Purpose of the Study:
- To compare the performance of individuals across the cardiovascular disease continuum on the MoCA and its subscores.
- To investigate the utility of the MoCA in identifying cognitive changes associated with different CVD profiles.
Main Methods:
- Eighty participants over 50 years old were categorized into four groups: low cardiovascular risk, high cardiovascular risk, coronary heart disease, and stable heart failure.
- Analysis of Variance (ANCOVA) was used to compare MoCA total and subscores, controlling for sex, age, and education.
Main Results:
- Significant differences were found in MoCA total scores, with heart failure patients scoring lower than those with low cardiovascular risk.
- Subscore analysis revealed deficits in verbal fluency (heart failure < low risk), memory (coronary heart disease < low risk), and orientation (coronary heart disease < low and high risk).
Conclusions:
- The MoCA, especially its verbal fluency and memory components, can identify cognitive changes in advanced cardiovascular disease stages like heart failure.
- Detecting cognitive impairment earlier in the cardiovascular disease continuum may necessitate comprehensive neuropsychological assessments beyond the MoCA.
Abstract:
Cardiovascular diseases involve a continuum starting with risk factors, which can progress to coronary heart disease and eventually, to heart failure. Cognitive impairment (CI) is observed as early as cardiovascular risk factors, and in up to 50% of patients with heart failure. Because CI in cardiovascular disease is linked to poorer clinical outcomes, early detection is essential. The Montreal Cognitive Assessment (MoCA) is a screening tool widely used in clinical setting. To date, little is known about MoCA scores along the cardiovascular disease continuum.
Objective:
This study compared performances of different cardiovascular disease profiles on the MoCA and its subscores.
Method:
Eighty participants (>50 years) from two studies conducted at the Montreal Heart Institute were separated into four groups: low cardiovascular risk factors (<2), high cardiovascular risk factors (>2), coronary heart disease, and stable heart failure. ANCOVAs were performed on the total score and on subscores, with sex, age, and education as covariates.
Results:
Group differences were observed on the MoCA total score (heart failure < low cardiovascular risk), verbal fluency (heart failure < low cardiovascular risk), memory (coronary heart disease < low cardiovascular risk), and orientation (coronary heart disease < low and high cardiovascular risk) subscores.
Conclusion:
Results suggest that the MoCA, particularly verbal fluency and memory subscores, can detect cognitive changes in later stages of the cardiovascular disease continuum, such as heart failure. Detecting cognitive changes earlier on the cardiovascular disease continuum may require more in depth neuropsychological assessments.
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