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Updated: Nov 6, 2025

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Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
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The Risks and Benefits of Myopia Control
Mark A Bullimore1, Eric R Ritchey1, Sunil Shah2
1College of Optometry, University of Houston, Houston, Texas.
Ophthalmology
|May 7, 2021
Summary
Slowing myopia progression is crucial for preventing future vision loss. The benefits of myopia control significantly outweigh the risks, with fewer than 1 in 38 experiencing vision loss from treatments.
Area of Science:
- Ophthalmology
- Optometry
- Public Health
Background:
- Globally increasing myopia prevalence necessitates effective progression control strategies.
- Slowing myopia progression aims to mitigate risks of sight-threatening ocular pathologies later in life.
- This study evaluates the risk-benefit profile of reducing myopia by 1 diopter (D).
Purpose of the Study:
- To analyze if the benefits of slowing myopia progression by 1D justify potential treatment risks.
- To quantify the risk of visual impairment from myopia control treatments.
- To review the increased risk of ocular conditions associated with higher myopia levels.
Main Methods:
- Summarizing risks of myopia control methods, focusing on contact lens wear.
- Estimating visual impairment risk and duration based on incidence data.
- Developing a model to predict visual impairment years versus myopia level and control efficacy.
Main Results:
- Each 1D increase in myopia elevates risks for myopic maculopathy, glaucoma, cataract, and retinal detachment.
- Between 38 and 945 patients require 5 years of treatment to cause 5 years of vision loss.
- A 1D reduction in myopia can decrease predicted visual impairment by 0.74 to 1.21 years.
Conclusions:
- The benefits of myopia control substantially outweigh the associated risks.
- The number needed to treat to prevent 5 years of visual impairment ranges from 4.1 to 6.8.
- Less than 1 in 38 individuals experience vision loss due to myopia control interventions.
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