Cardiac dysfunction associated with the acquired immunodeficiency syndrome (AIDS)
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Updated: Sep 30, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
J G Webb1, C Chan-Yan, M C Kiess
1Department of Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, Canada.
Abstract:
Five patients with acquired immune deficiency syndrome (AIDS) developed clinical evidence of mild to severe cardiac dysfunction confirmed by nuclear angiography and echocardiography. In 4 patients who were studied postmortem there was no evidence of myocarditis, valvular, or ischemic heart disease. Cardiac involvement in patients with AIDS may include pericardial and myocardial involvement by opportunistic pathogens or Kaposi's sarcoma, subclinical myocardial dysfunction, or an as-yet unexplained cardiomyopathy.
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