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Related Concept Videos

Exercise and Muscle Performance01:27

Exercise and Muscle Performance

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Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
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Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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Plain language summary of publication of how long people with relapsed multiple myeloma lived after treatment in the IKEMA study: Isatuximab plus carfilzomib and dexamethasone versus carfilzomib and dexamethasone.

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Related Experiment Video

Updated: Nov 6, 2025

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Multiple myeloma and physical activity.

Catherine S Y Lecat1, Orla McCourt2,3, Joanne Land4

  • 1University College London Cancer Institute, 72 Huntley Street, London, WC1E 6DD, UK. Catherine.lecat@nhs.net.

BMC Research Notes
|May 8, 2021
PubMed
Summary
This summary is machine-generated.

Most multiple myeloma patients desire more physical activity but face barriers like fatigue and pain. Exercise significantly improves their quality of life, indicating a need for tailored programs.

Keywords:
ExerciseMultiple myelomaPhysical activity

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Area of Science:

  • Oncology
  • Exercise Science
  • Patient-Reported Outcomes

Background:

  • Physical activity is recognized for enhancing quality of life in cancer patients.
  • Evidence suggests benefits of exercise for multiple myeloma patients.
  • Understanding current exercise levels and perceptions is crucial for supportive care.

Purpose of the Study:

  • To assess exercise levels among multiple myeloma outpatients.
  • To evaluate patients' perceptions and barriers regarding physical activity.
  • To explore the correlation between physical activity and quality of life.

Main Methods:

  • A cohort of multiple myeloma outpatients completed questionnaires.
  • The Godin leisure-time exercise questionnaire (GLTEQ) measured exercise levels.
  • The Functional Assessment of Cancer Therapy-General (FACT-G) and FACIT-F assessed quality of life and fatigue.

Main Results:

  • Only 25% of respondents met activity criteria based on GLTEQ scores.
  • A significant positive correlation was found between exercise levels (GLTEQ) and quality of life (FACT-G) (p < 0.001).
  • Weakness, fatigue, and pain were primary perceived barriers; 75% wished to increase activity and 59% desired advice.

Conclusions:

  • Multiple myeloma patients exhibit an unmet need for physical activity.
  • Current care models may not adequately address exercise needs.
  • Integrating tailored exercise advice and programs is recommended for holistic patient care.