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Plexiform trigeminal neurofibroma.

A Gholkar1, J P Stack, I Isherwood

  • 1Department of Diagnostic Radiology, University of Manchester.

Clinical Radiology
|May 1, 1988
PubMed
Summary
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Neurofibromas of the trigeminal nerve are rare tumors typically seen in adults. This case highlights an unusual presentation of a plexiform neurofibroma, offering new insights into these uncommon cranial nerve tumors.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Pathology

Background:

  • Neurofibromas, benign nerve sheath tumors, can affect cranial nerves.
  • Trigeminal nerve neurofibromas are uncommon, usually presenting in the third or fourth decade.
  • These tumors typically manifest as localized masses within the cranial fossae.

Observation:

  • A case of a plexiform neurofibroma involving the trigeminal nerve is presented.
  • This specific case exhibited atypical clinical and radiological characteristics.
  • Plexiform neurofibromas are complex, diffuse tumors often associated with genetic syndromes.

Findings:

  • The presented case demonstrates unusual features not commonly associated with trigeminal nerve neurofibromas.
  • Detailed radiological analysis revealed unique spatial characteristics of the tumor.

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  • Histopathological examination confirmed the plexiform subtype with specific cellular arrangements.

    • Implications:

    • This case expands the understanding of the clinical and radiological spectrum of trigeminal nerve neurofibromas.
    • It underscores the importance of considering rare presentations in diagnosis and treatment planning.
    • Further research into the specific genetic and molecular underpinnings of such unusual presentations may be warranted.