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Related Concept Videos

Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Antimicrobial stewardship solutions with a smart innovative tool.

May A Shawki, Watheq M AlSetohy, Kareem A Ali

    Journal of the American Pharmacists Association : Japha
    |May 8, 2021
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    Summary

    A mobile app effectively reduced antimicrobial consumption and mortality rates in a hospital setting. This intervention also led to significant cost savings and improved detection of drug-related problems.

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    Area of Science:

    • Health Informatics
    • Infectious Diseases
    • Hospital Management

    Background:

    • Rising antimicrobial consumption necessitates effective strategies to combat antimicrobial resistance.
    • Antimicrobial stewardship programs (ASPs) are crucial for optimizing antimicrobial use.
    • Developing innovative tools is essential for enhancing ASP implementation.

    Purpose of the Study:

    • To assess the impact of a mobile application on the implementation of antimicrobial stewardship program (ASP) interventions.
    • To evaluate the effectiveness of a mobile app in promoting rational antimicrobial use among healthcare professionals.

    Main Methods:

    • A longitudinal study was conducted in a Cairo hospital from January 2018 to December 2019.
    • The study compared a paper-based ASP (preimplementation phase) with a mobile app-based ASP (MEDIcare Pro app).
    • Key outcomes included antimicrobial consumption, costs, length of stay, mortality, readmission rates, and drug-related problems (DRPs).

    Main Results:

    • The mobile app significantly decreased antimicrobial consumption (75.1 to 64.65 DDD/100 bed-days) and associated costs (E£1,237,476 savings).
    • A significant reduction in intensive care unit (ICU) length of stay (1.63 days) and mortality rate (1.17% to 0.83%) was observed.
    • The detection of drug-related problems (DRPs) by pharmacists significantly increased (0.54 to 3.23/100 bed-days).

    Conclusions:

    • Mobile applications are effective, applicable, and usable tools for guiding rational antimicrobial use.
    • Implementing mobile apps can enhance antimicrobial stewardship programs and improve patient outcomes.
    • This technology offers a promising approach to control antimicrobial use and mitigate resistance.