Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cyst-ained connections in the mammalian germline.

Current topics in developmental biology·2026

Same author

Assessment of hepatitis C virus permissiveness in iteratively genetically humanized mice.

Journal of virology·2025

Same author

Generative model for the first cell fate bifurcation in mammalian development.

Development (Cambridge, England)·2025

Same author

Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation.

Current biology : CB·2025

Same author

A live-cell biosensor of in vivo receptor tyrosine kinase activity reveals feedback regulation of a developmental gradient.

Cell reports·2025

Same author

Geometric, cell cycle and maternal-to-zygotic transition-associated YAP dynamics during preimplantation embryo development.

Developmental biology·2025

Same journal

Anisotropic unbinding and location-dependent hovering of a kinesin motor head over microtubule.

Biophysical journal·2026

Same journal

Kinesin-5/Cut7 C-terminal tail phosphorylation influence on motor regulation through multi-scale molecular modeling.

Biophysical journal·2026

Same journal

Dynamic conformations of fluorophores on self-labeling protein tags.

Biophysical journal·2026

Same journal

Different actions of RyR2 open and closed channel block explained by a multiscale Ca<sup>2+</sup> release model.

Biophysical journal·2026

Same journal

Membrane Environment Sets the Functional pK<sub>a</sub> of Ionizable Lipids.

Biophysical journal·2026

Same journal

Distinguishable spreading dynamics in microbial communities.

Biophysical journal·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 6, 2025

Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

Published on: June 4, 2014

Imaging developmental cell cycles.

Abraham Q Kohrman¹, Rebecca P Kim-Yip¹, Eszter Posfai¹

¹Department of Molecular Biology, Princeton University, Princeton, New Jersey.

Biophysical Journal

|May 8, 2021

Summary

This summary is machine-generated.

Live biosensors and advanced microscopy enable new discoveries in cell cycle research. This review covers tools for visualizing the cell cycle and tracking cellular behavior, paving the way for developmental biology insights.

More Related Videos

Analysis of Cell Cycle Position in Mammalian Cells

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics

Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics

Published on: September 14, 2015

Related Experiment Videos

Last Updated: Nov 6, 2025

Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

Published on: June 4, 2014

Analysis of Cell Cycle Position in Mammalian Cells

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics

Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics

Published on: September 14, 2015

Area of Science:

Cellular Biology
Developmental Biology
Microscopy

Background:

Significant advancements in live biosensor development and genetic encoding in model organisms over the past decade.
Integration of biosensors with microscopy techniques provides powerful tools for biological discovery.

Purpose of the Study:

To review the current availability of biosensors for visualizing the cell cycle.
To summarize techniques for single-cell tracking and quantification of cell cycle reporters.
To highlight research connecting cellular behavior to the cell cycle using live imaging.

Main Methods:

Live biosensor development and genetic encoding.
Advanced microscopy techniques for visualization.
Single-cell tracking and reporter quantification.

Main Results:

Availability of diverse biosensors for cell cycle visualization.
Established techniques for quantitative analysis of cell cycle reporters.
Emerging studies linking cellular behavior to cell cycle progression via live imaging.

Conclusions:

The combination of live biosensors, genetic encoding, and microscopy offers unprecedented opportunities for fundamental biological discoveries.
Future research is expected to yield significant insights into developmental processes through these integrated technologies.