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Effects of Physiologic Myopia and Aging on Visual Fields in Normal Eyes
Aiko Iwase1, Makoto Fujii2, Hiroshi Murata3
1From the Tajimi Iwase Eye Clinic, Gifu, Japan (A.I.).
American Journal of Ophthalmology
|May 9, 2021
Summary
Visual field sensitivity (VF-S) decreases with age in normal eyes, particularly in the midperiphery. Axial length (AL) impacts VF-S independently of age, but does not significantly affect age-related decline.
Area of Science:
- Ophthalmology
- Visual Neuroscience
Background:
- Visual field sensitivity (VF-S) is crucial for visual function.
- Aging and myopia are known factors that can influence visual perception.
- Understanding their independent and combined effects on VF-S is important for diagnosing and managing visual impairments.
Purpose of the Study:
- To investigate the effects of mild-to-moderate myopia and aging on VF-S in normal eyes.
- To differentiate the impact of each factor on visual field sensitivity.
- To analyze age-related changes in VF-S and their correlation with axial length (AL).
Main Methods:
- A combined cross-sectional and cohort study design was employed.
- Two groups of normal subjects were included: a cross-sectional group (n=703) and a longitudinal group (n=44).
- Linear mixed-regression models were used to correlate VF-S with age, AL, ocular parameters, and time.
Main Results:
- VF-S showed a negative correlation with age, with a more pronounced decline in the midperipheral subfield.
- Axial length (AL) was negatively correlated with VF-S, independent of age.
- In the longitudinal group, VF-S declined annually, accelerating with higher age and baseline VF-S, unrelated to ocular media changes.
Conclusions:
- In normal eyes with mild-to-moderate myopia, longer AL is associated with lower VF-S.
- Aging leads to a reduction in VF-S, with intersubfield differences observed.
- The age-associated decline in VF-S accelerates with increasing age and is not influenced by ocular media changes or axial length.
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