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Association between functional status at hospital discharge and long-term survival after

Richard Chocron1, Carol Fahrenbruch2, Lihua Yin2

  • 1Paris University, Paris Research Cardiovascular Center (PARCC), INSERM, F-75015 Paris, France; Emergency Department, AP-HP, Georges Pompidou European Hospital, F-75015 Paris, France.

Resuscitation
|May 9, 2021
PubMed

Insights

The Cerebral Performance Category (CPC) and modified Rankin Scale (mRS) both predict long-term survival in out-of-hospital cardiac arrest (OHCA) survivors. A consolidated mRS score may simplify prognostic assessments.

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Out-of-hospital cardiac arrest (OHCA) survivors often experience brain injury.
  • Assessing functional status post-discharge is crucial for resuscitation outcomes.
  • Cerebral Performance Category (CPC) and modified Rankin Scale (mRS) are commonly used scales.

Purpose of the Study:

  • To compare the predictive accuracy of CPC and mRS for long-term survival in OHCA survivors.
  • To determine which scale better predicts mortality after hospital discharge.

Main Methods:

  • Retrospective cohort study of OHCA survivors (2007-2015).
  • Utilized regional quality improvement registry (CPC) and research studies (mRS).
  • Kaplan-Meier analysis and Cox proportional hazards regression were used to estimate mortality risk.

Main Results:

  • 878 patients were discharged alive; 358 deaths occurred over 9118.5 person-years.
  • 1, 5, and 10-year survival rates were 84.4%, 68.5%, and 53.7%, respectively.
  • Both CPC and mRS categories showed significant associations with mortality risk (p < 0.01).

Conclusions:

  • Both CPC and mRS scales effectively predict long-term survival in OHCA survivors.
  • The mRS scale showed overlapping prognoses for mRS 0-1 and 2-3 categories.
  • Consolidating mRS scores could simplify the capture of prognostic information.
Abstract

Keywords:
Long-term survivalNeurological outcomeOut of hospital cardiac arrestPrognosticationQuality in health care

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