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Updated: Nov 6, 2025

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices
Published on: May 9, 2018
Labelling and denominating lung toxicity effects of pesticides
1Food Claims Centre Venlo, Campus Venlo, Faculty of Science and Engineering, Maastricht University, Venlo, The Netherlands.
Purpose Of Review:
With the development and use of pesticide products increasing, information on the safe handling of pesticides becomes increasingly important. In this article, the denomination of lung toxicity on labelling is reviewed.
Recent Findings:
The results highlight that whereas hazards, warning statements and instructions for safe use are broadly defined, the different categories of products used as pesticides are associated with different types of clinical manifestations of toxicity. These clinical manifestations are however not directly warned for by means of information provided on the label: more overarching terminology is used to describe hazards associated with acute toxicity, respiratory sensitization, specific lung toxicity after single or repeated exposure, as well as hazards from aspiration.
Summary:
This misalignment between hazard labelling and experienced issues increases the difficulty for users of products and clinicians in dealing with adverse events. Together with ensuring that in risk assessment, an integrated approach is taken to study pesticide products, improving the labels will support the safe handling of pesticides.
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