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Polypharmacy among psychiatric patients.

E Hemminki

    Acta Psychiatrica Scandinavica
    |November 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Psychiatric polypharmacy is common in Helsinki, with 69% of patients receiving multiple psychotropic drugs. Clinical trial evidence does not support this frequent polypharmacy, suggesting a need for reduction.

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    Area of Science:

    • Psychiatry
    • Clinical Pharmacology

    Background:

    • Polypharmacy, the concurrent use of multiple medications, is prevalent in psychiatric care.
    • The clinical trial evidence supporting psychotropic polypharmacy is often limited.

    Purpose of the Study:

    • To determine the frequency of polypharmacy among psychiatric patients in Helsinki.
    • To evaluate the clinical trial support for psychotropic polypharmacy.

    Main Methods:

    • A sample of 694 psychiatric patients from Helsinki's mental hospitals and outpatient clinics were analyzed.
    • A review of controlled clinical trials on the simultaneous use of multiple psychotropic drugs was conducted.

    Main Results:

    • 69% of patients received more than one psychotropic drug daily; 61% received "proper" psychotropic drugs.

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  • An average of 2.1 different psychotropic drugs were prescribed per patient, with a maximum of 6.
  • Only 3 out of 14 reviewed clinical trials found polypharmacy superior to single drug treatments or placebo.

    • Conclusions:

    • The frequent use of polypharmacy in psychiatric patients in Helsinki is not well-supported by existing clinical trial evidence.
    • A significant reduction in prescribed psychotropic drugs for psychiatric patients appears warranted.