Related Experiment Video
Updated: Nov 6, 2025
10:12
Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
Published on: May 23, 2013
16.1K
Audio-vestibular Abnormalities in Patients With Vitiligo: A Prospective Case-control Study
Reham Mamdouh Lasheen1, Mohamed Nasser Elsheikh, Mohamed M Fawzy
1Faculty of Medicine, Tanta University, Tanta, Egypt.
Summary
Vitiligo patients often experience hearing loss, particularly at high frequencies. This study highlights the impact of vitiligo on the audio-vestibular system, emphasizing the need for early screening.
Area of Science:
- Oto-neurology
- Dermatology
- Audiology
Background:
- Vitiligo is a condition causing melanocyte loss throughout the body, including the inner ear.
- Melanocyte deficits may impact the audio-vestibular system.
Purpose of the Study:
- To investigate the effects of reduced melanocytes in vitiligo patients on audio-vestibular function.
- To compare audiological and vestibular assessments between vitiligo patients and healthy controls.
Main Methods:
- Included 35 vitiligo patients and 35 healthy controls.
- Assessed auditory function via pure-tone audiometry and auditory brainstem response (ABR).
- Evaluated vestibular function using Dizziness Handicap Inventory, cervical vestibular-evoked myogenic potential (cVEMP), and videonystagmography.
Main Results:
- 12 vitiligo patients exhibited hearing impairment, especially in high frequencies.
- Prolonged ABR wave III and I-III inter-peak latencies were observed in vitiligo patients.
- Delayed cVEMP waves (P13, N23) and vestibular weakness (unilateral or bilateral) were noted in some vitiligo patients.
Conclusions:
- Vitiligo is a systemic disease that can affect the audio-vestibular system.
- Early screening for audio-vestibular changes is crucial in vitiligo patients.
- Vitiligo patients are more vulnerable to ototoxic damage, noise, and age-related hearing loss.
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