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Hepatitis C virus micro-elimination: Where do we stand?

Alessandra Mangia1, Rosa Cotugno2, Giovanna Cocomazzi2

  • 1Liver Unit, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo 71013, Fg, Italy. a.mangia@tin.it.

World Journal of Gastroenterology
|May 10, 2021
PubMed
Summary
This summary is machine-generated.

Hepatitis C virus (HCV) elimination goals are challenged by the pandemic. A micro-elimination strategy, targeting specific populations and settings, offers a realistic alternative for HCV eradication.

Keywords:
Hepatitis C virus RNAHepatitis C virus antibodiesHepatitis C virus diagnosisHepatitis C virus eliminationHepatitis C virus epidemiologyHepatitis C virus infection

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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health

Background:

  • The World Health Organization's goal of Hepatitis C virus (HCV) elimination by 2030 faces significant challenges.
  • The COVID-19 pandemic has further hindered global HCV eradication efforts, necessitating revised strategies.

Purpose of the Study:

  • To propose micro-elimination as a feasible alternative strategy for Hepatitis C virus (HCV) eradication.
  • To outline the principles and components of successful micro-elimination projects.

Main Methods:

  • The study reviews the concept of micro-elimination for HCV.
  • It identifies target populations, settings (e.g., prisons, hospitals), and geographical considerations for tailored strategies.
  • Key elements for successful implementation are discussed.

Main Results:

  • Micro-elimination focuses on achieving HCV elimination in smaller, defined segments of the population.
  • This approach allows for targeted prevention and treatment strategies.
  • Successful micro-elimination can contribute to broader, macro-elimination goals.

Conclusions:

  • Micro-elimination represents a pragmatic and achievable approach to combatting Hepatitis C virus (HCV) in the post-pandemic era.
  • Reliable data, stakeholder engagement, and community involvement are crucial for the success of micro-elimination initiatives.
  • This strategy offers a viable path towards regional and global HCV elimination.