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The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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Association between Thyroiditis and Multifocality in Papillary Thyroid Carcinoma.

Rogério Aparecido Dedivitis^1,2, Leandro Luongo de Matos^1,3, Felipe Guilherme Silva Souza⁴

¹Department of Surgery, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

International Archives of Otorhinolaryngology

|May 10, 2021

Summary

This summary is machine-generated.

Hashimoto thyroiditis (HT) does not appear to be related to multifocal papillary thyroid carcinoma (PTC). This study found no direct link between HT and the multifocal pattern or cervical extension of PTC.

Keywords:

papillary thyroid carcinoma thyroid cancer thyroiditis

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Area of Science:

Endocrinology
Oncology
Pathology

Background:

Hashimoto thyroiditis (HT) shares clinical and pathological similarities with papillary thyroid carcinoma (PTC).
Previous research suggests a potential association between HT and multifocal PTC, often with smaller lesions.

Purpose of the Study:

To investigate the relationship between Hashimoto thyroiditis and papillary thyroid carcinoma.
To determine if HT influences the multifocal pattern or cervical extension of PTC.

Main Methods:

Retrospective analysis of 155 patients who underwent total thyroidectomy between 2009 and 2015.
Evaluation of demographical, clinical, ultrasonographical, and anatomopathological data.
Statistical analysis to assess correlations between thyroiditis, lesion characteristics, and disease extension.

Main Results:

Thyroiditis was present in 35 patients; 114 had unifocal disease.
No statistical significance was found between variables studied and thyroiditis.
No direct relationship was observed between thyroiditis and multifocality (p=0.325) or cervical extension (p=0.300, p=0.434) in PTC cases.

Conclusions:

The study found no evidence to support a relationship between Hashimoto thyroiditis and multifocality in papillary thyroid carcinoma.
Further research may be needed to fully elucidate the complex interplay between these thyroid conditions.