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Related Experiment Video

Updated: Nov 6, 2025

Author Spotlight: The Significance of Isolation, Culture, and Adipogenic Induction of SVF-Derived Preadipocytes from Mouse Perivascular Adipose Tissue

Author Spotlight: The Significance of Isolation, Culture, and Adipogenic Induction of SVF-Derived Preadipocytes from Mouse Perivascular Adipose Tissue

Published on: July 21, 2023

Association Between Epicardial Adipose Tissue and Stroke.

Maria Inês Rosa¹, Antonio José Grande², Leticia Dorsa Lima²

¹Laboratory of Biomedicine Translational, University of Extremo Sul Catarinense, Criciúma, Brazil.

Frontiers in Cardiovascular Medicine

|May 10, 2021

Summary

Increased epicardial fat thickness (EFT) may link to stroke risk, particularly with metabolic syndrome and atrial fibrillation. Further research is needed to clarify the exact connection between epicardial adipose tissue (EAT) and stroke incidence.

Keywords:

atherosclerosis epicardial adipose tissue metabolic syndrome stroke systematic review

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The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens

Published on: April 24, 2018

Area of Science:

Cardiology
Neurology
Medical Imaging

Background:

Epicardial adipose tissue (EAT) is linked to cardiovascular risks, including endothelial dysfunction and metabolic syndrome.
Emerging evidence suggests a potential association between EAT and an increased risk of stroke.
Understanding this relationship is crucial for stroke prevention strategies.

Approach:

A systematic review was conducted to evaluate studies assessing the association between EAT and stroke.
Eighty relevant studies were identified and analyzed.
The review assessed the quality of evidence and identified limitations in existing research.

Key Points:

Increased epicardial fat thickness (EFT) shows a potential association with stroke episodes.
This association is consistent across various imaging modalities like echocardiography, MRI, and CT.
Co-existing conditions such as metabolic syndrome and atrial fibrillation appear to amplify stroke risk.

Conclusions:

While a clear causal link between EAT and stroke remains elusive, this review consolidates current evidence.
The mechanistic pathways connecting increased EAT to stroke incidence require further investigation.
Future research should address identified limitations to provide more definitive insights.