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Updated: Nov 6, 2025

Rapid Lipid Droplet Isolation Protocol Using a Well-established Organelle Isolation Kit
Published on: April 19, 2019
Successful plasmapheresis and immunoglobulin treatment for severe lipid storage myopathy: Doing the right thing for
Felix Kleefeld1, Anja von Renesse2, Carsten Dittmayer3
1Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Abstract:
Three consecutive skeletal muscle biopsies during a several months time-frame, showing different degrees of neutral lipid storage. This is highlighted by Oil-red-O stains (D, E, F) and electron microscopy (G, H, I). Note the impact on mitochondrial morphology with so called 'parking lots (K, L). Zooming 'in and out' into the ultrastructure, using the nanotomy platform provides interesting detailled information (http://nanotomy.org). .
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