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Updated: Nov 6, 2025

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Aortic Root Replacement With Autologous Pericardium Valved Conduit.
Laura Seese1, Pyongsoo Yoon2, Victor O Morell2
1Department of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
This study presents a novel aortic valve replacement technique using autologous pericardium, offering excellent outcomes and avoiding long-term anticoagulation. This innovative approach addresses challenges in current aortic prosthesis options for improved patient durability.
Area of Science:
- Cardiac Surgery
- Biomaterials in Medicine
- Aortic Valve Repair and Replacement
Background:
- Current aortic prosthesis options face challenges in minimizing perioperative morbidity, pressure gradients, and ensuring long-term durability.
- Trileaflet aortic valve reconstruction with autologous pericardium shows promise as an alternative, offering good postoperative gradients and avoiding anticoagulation.
Purpose of the Study:
- To introduce a novel adaptation of the modified Bentall procedure.
- To utilize a self-fabricated valved conduit with trileaflet aortic valve neocuspidization using autologous pericardium.
Main Methods:
- Adaptation of the modified Bentall procedure.
- Creation of a self-fabricated valved conduit.
- Trileaflet aortic valve neocuspidization using autologous pericardium.
Main Results:
- The novel technique aims to achieve excellent postoperative gradients and large effective orifice areas.
- This method avoids the need for long-term anticoagulation, a significant advantage over traditional prostheses.
Conclusions:
- The described self-fabricated pericardial valved conduit represents a promising alternative for aortic root replacement.
- This innovative approach may overcome limitations of current aortic valve replacement strategies, enhancing patient outcomes and durability.
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