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Pharmacy-assisted burn unit skin bank program.

L W Roberts, J O'Donnell, T Matsuda

    American Journal of Hospital Pharmacy
    |December 1, 1977
    PubMed
    Summary
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    Pharmacy services developed a sterile fluid to preserve homograft skin from cadavers. This process is crucial for skin banking, ensuring viable tissue for transplantation and patient recovery.

    Area of Science:

    • Tissue banking and preservation science.
    • Sterile pharmaceutical product development.
    • Transplantation medicine.

    Background:

    • Homograft skin transplantation requires specialized preservation techniques.
    • Cadaver donation is a vital source for skin grafts.
    • Pharmacy services play a role in sterile fluid development.

    Purpose of the Study:

    • To describe the development and production of a sterile preservation fluid for homograft skin.
    • To outline the essential considerations for establishing and maintaining a skin bank.
    • To detail the use of pharmacy services in sterile fluid preparation.

    Main Methods:

    • Formulation of a sterile skin bank fluid.
    • Sterile production and storage protocols for the preservation fluid.

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  • Evaluation of fluid for preservation of harvested homograft skin.

    • Main Results:

    • Successful development of a sterile fluid for homograft skin preservation.
    • Established protocols for fluid production, storage, and use.
    • Defined criteria for acceptable cadaver donors and indications for homograft use.

    Conclusions:

    • Pharmacy services are integral to the successful development and production of sterile preservation fluids for skin banking.
    • Proper formulation, production, and storage of sterile fluids are critical for maintaining homograft viability.
    • Standardized protocols enhance the safety and efficacy of homograft skin transplantation.