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A dermatologic perspective on multisystem inflammatory syndrome in children.
Fludiona Naka1, Laura Melnick1, Mark Gorelik2
1Department of Dermatology, Columbia University Medical Center, New York, New York, USA.
Clinics in Dermatology
|May 11, 2021
Summary
Multisystem inflammatory syndrome in children (MIS-C) is a new condition linked to COVID-19, primarily affecting children. This review focuses on understanding MIS-C, particularly its mucocutaneous symptoms.
Area of Science:
- Pediatrics
- Infectious Diseases
- Immunology
Background:
- An emerging immune-mediated syndrome, multisystem inflammatory syndrome in children (MIS-C), has been identified in children.
- MIS-C is associated with coronavirus disease 2019 (COVID-19) and appears weeks after initial infection.
Purpose of the Study:
- To review recent data on MIS-C.
- To enhance understanding of MIS-C, focusing on its mucocutaneous manifestations.
Main Methods:
- Literature review of recently published data on MIS-C.
- Analysis of clinical presentations and features of MIS-C.
Main Results:
- MIS-C presents with prolonged fever, skin rash, neck stiffness, and gastrointestinal issues.
- Shock and organ dysfunction can occur, but respiratory distress is typically absent.
- Mucocutaneous manifestations are a key feature of MIS-C.
Conclusions:
- MIS-C is a significant pediatric condition associated with COVID-19.
- Understanding the mucocutaneous features of MIS-C is crucial for diagnosis and management.
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