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Hypopituitarism presenting as delirium.

S Khanna1, A Ammini, S Saxena

  • 1National Institute of Mental Health and Neurosciences, Banglaore, India.

International Journal of Psychiatry in Medicine
|January 1, 1988
PubMed
Summary
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Sheehan's Syndrome, a rare hypopituitarism after childbirth, can manifest as delirium. Prompt diagnosis and hormonal therapy led to sustained symptom remission in this case.

Area of Science:

  • Endocrinology
  • Neurology
  • Obstetrics

Background:

  • Sheehan's Syndrome is a rare complication of postpartum hemorrhage causing pituitary necrosis.
  • Hypopituitarism can present with diverse neurological symptoms, including delirium.
  • Early recognition is crucial for timely management and preventing long-term sequelae.

Observation:

  • A postpartum patient presented with acute delirium.
  • Clinical suspicion for hypopituitarism was raised due to the presentation.
  • The patient had a history suggestive of postpartum complications.

Findings:

  • Diagnosis of hypopituitarism was confirmed using pituitary stimulation tests.
  • The patient's delirium resolved with appropriate hormonal replacement therapy.

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  • Symptom-free status was maintained for three years on maintenance therapy.
  • Implications:

    • This case highlights the importance of considering hypopituitarism in postpartum delirium.
    • Effective management of Sheehan's Syndrome can lead to complete recovery and sustained well-being.
    • Highlights the critical role of endocrine assessment in postpartum neurological presentations.