Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

284
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
284
Causality in Epidemiology01:21

Causality in Epidemiology

1.2K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.2K
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

285
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
285
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

4.2K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
4.2K
Interpreting Run Charts01:25

Interpreting Run Charts

2.9K
Run charts, essentially line graphs plotted over time, serve as fundamental yet effective tools for process analysis. They chronicle data sequentially, facilitating the identification of trends, shifts, or cyclical movements. This graphical representation is instrumental in determining whether a process is stable or exhibits signs of potential instability indicative of special cause variation. In the healthcare domain, run charts depict infection rates over time, enabling hospitals to monitor...
2.9K
Introduction to Epidemiology01:26

Introduction to Epidemiology

1.2K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sustainability as a challenge in complex systems dynamics.

Nature computational science·2026
Same author

Aging and memory of transitional turbulence.

Nature communications·2025
Same author

Extreme synchronization transitions.

Nature communications·2025
Same author

Learning the dynamics of symmetry-reduced chaotic attractors from data.

Chaos (Woodbury, N.Y.)·2025
Same author

Perturbation-response dynamics of coupled nonlinear systems.

Chaos (Woodbury, N.Y.)·2024
Same author

Efficient self-organization of informal public transport networks.

Nature communications·2024

Related Experiment Video

Updated: Nov 6, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
08:26

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

1.9K

Discontinuous epidemic transition due to limited testing.

Davide Scarselli1, Nazmi Burak Budanur1, Marc Timme2

  • 1Institute of Science and Technology Austria, Klosterneuburg, Austria.

Nature Communications
|May 11, 2021
PubMed
Summary

Limited testing capacity can cause epidemic containment measures to fail dramatically. Initial suppression may lead to explosive, faster-than-exponential growth, posing significant risks during outbreaks.

More Related Videos

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.3K
Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.1K

Related Experiment Videos

Last Updated: Nov 6, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
08:26

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

1.9K
Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.3K
Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.1K

Area of Science:

  • Epidemiology
  • Public Health
  • Mathematical Modeling

Background:

  • High-impact epidemics pose a significant global threat.
  • Non-pharmaceutical interventions like physical distancing, testing, and contact tracing are vital for epidemic control.
  • Limited testing capacity can undermine the effectiveness of these measures.

Purpose of the Study:

  • To investigate the impact of limited testing capacity on epidemic containment strategies.
  • To analyze how reduced testing alters epidemic transition dynamics.
  • To understand the potential for catastrophic failure of containment measures.

Main Methods:

  • Mathematical modeling of epidemic dynamics.
  • Analysis of discontinuous versus continuous responses to interventions.
  • Simulation of outbreak scenarios with varying testing capacities.

Main Results:

  • Limited testing transforms epidemic response from continuous to discontinuous.
  • Strong initial suppression can lead to accelerated, faster-than-exponential growth.
  • Containment measures face a critical threshold: success at low case numbers or catastrophic failure.

Conclusions:

  • Containment strategies are highly sensitive to testing capacity limitations.
  • Uncertainty in epidemic dynamics increases significantly with reduced testing.
  • Effective epidemic control requires robust and scalable testing infrastructure.